Drugs of abuse extraction from oral fluid using supported liquid extraction (SLE) following collection with NeoSal prior to GC/MS analysis
Author(s)
Biotage

Screening drugs of abuse can be complicated due to the wide variation of functional groups associated with different analyte classes. Most extraction techniques cannot extract all analytes using a single procedure without using non-optimal extraction protocols, resulting in compromised extract cleanliness. Supported liquid extraction allows for the simultaneous analysis of cross-functional analytes in a single extraction protocol without forfeiting extract cleanliness.

This poster demonstrates protocols for the determination of a range of drugs of abuse following collection with the NeoSal oral fluid device and GC/MS analysis. The drug suites included amphetamines and synthetic cathinones, barbiturates, benzodiazepines, cocaine, opiates, cannabinoids and synthetic cannabinoids.