ISOLUTE SLE+ Supported Liquid Extraction plates and columns offer an efficient alternative to traditional liquid-liquid extraction (LLE) for bioanalytical sample preparation, providing high analyte recoveries, no emulsion formation and significantly reduced sample preparation time.

This application note describes the extraction of neutral and zwitterionic antiepileptic drugs fortified in serum and urine using ISOLUTE SLE+ in a 96-well plate format.