Extraction of synthetic cannabinoids (SPICE) and metabolites from urine, plasma and whole blood using ISOLUTE SLE+ prior to LC-MS/MS analysis
Author(s)
Biotage

ISOLUTE SLE+ Supported Liquid Extraction plates and columns offer an efficient alternative to traditional liquid-liquid extraction (LLE) for bioanalytical sample preparation, providing high analyte recoveries, no emulsion formation and significantly reduced sample preparation time.

This application note describes the extraction and quantitation of cannabimimetic naphthoylindoles (synthetic cannabinoids) and their metabolites (JWH series) from various matrices using Supported Liquid Extraction (SLE).