Biotage ISOLUTE SLE+ supported liquid extraction plates and columns are designed to provide stress free extraction of analytes from biological fluids, with high analyte recoveries, and clean, protein and phospholipid free extracts. Methods are easy to develop and automation is simple.

This application note describes the fully-automated extraction of opiates from acid-hydrolyzed urine and non-hydrolyzed urine prior to GC/MS analysis. The methods were automated using Biotage Extrahera configured for use with ISOLUTE SLE+ supported liquid extraction columns.